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Magnesium supplementation therapy to prevent cisplatin-induced acute nephrotoxicity in pediatric cancer: A protocol for a randomized phase 2 trial

Although cisplatin is one of the most effective agents against various pediatric cancers, it is sometimes difficult to manage due to its dose-limiting nephrotoxicity. Magnesium sulfate (Mg) showed a kidney-protective effect against cisplatin-induced nephrotoxicity (CIN) by regulating renal platinum...

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Detalles Bibliográficos
Autores principales: Makimoto, Atsushi, Matsui, Motohiro, Chin, Motoaki, Koh, Katsuyoshi, Tomotsune, Masako, Kaneko, Tetsuji, Morikawa, Yoshihiko, Yuza, Yuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722396/
https://www.ncbi.nlm.nih.gov/pubmed/31508533
http://dx.doi.org/10.1016/j.conctc.2019.100440