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A high-throughput, bead-based, antigen-specific assay to assess the ability of antibodies to induce complement activation()

The complement system plays a critical role in innate immune defense against pathogens, both via non-specific direct pathogen recognition and killing or via antigen-specific indirect recruitment by complement fixing antibodies. While various assays for measuring complement activation have been devel...

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Detalles Bibliográficos
Autores principales: Fischinger, Stephanie, Fallon, Jonathan K., Michell, Ashlin R., Broge, Thomas, Suscovich, Todd J., Streeck, Hendrik, Alter, Galit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722412/
https://www.ncbi.nlm.nih.gov/pubmed/31301278
http://dx.doi.org/10.1016/j.jim.2019.07.002