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A high-throughput, bead-based, antigen-specific assay to assess the ability of antibodies to induce complement activation()
The complement system plays a critical role in innate immune defense against pathogens, both via non-specific direct pathogen recognition and killing or via antigen-specific indirect recruitment by complement fixing antibodies. While various assays for measuring complement activation have been devel...
Autores principales: | Fischinger, Stephanie, Fallon, Jonathan K., Michell, Ashlin R., Broge, Thomas, Suscovich, Todd J., Streeck, Hendrik, Alter, Galit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722412/ https://www.ncbi.nlm.nih.gov/pubmed/31301278 http://dx.doi.org/10.1016/j.jim.2019.07.002 |
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