Human FcRn Tissue Expression Profile and Half-Life in PBMCs

System-wide quantitative characterization of human neonatal Fc receptor (FcRn) properties is critical for understanding and predicting human PK (pharmacokinetics) as well as the distribution of mAbs and Fc-fusion proteins using PBPK (physiologically-based pharmacokinetic) modeling. To this end, tiss...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Yao-Yun, Farrokhi, Vahid, Caiazzo, Teresa, Wang, Mengmeng, O’Hara, Denise M., Neubert, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722552/
https://www.ncbi.nlm.nih.gov/pubmed/31443181
http://dx.doi.org/10.3390/biom9080373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722552/
https://www.ncbi.nlm.nih.gov/pubmed/31443181
http://dx.doi.org/10.3390/biom9080373

Ejemplares similares