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Human FcRn Tissue Expression Profile and Half-Life in PBMCs

System-wide quantitative characterization of human neonatal Fc receptor (FcRn) properties is critical for understanding and predicting human PK (pharmacokinetics) as well as the distribution of mAbs and Fc-fusion proteins using PBPK (physiologically-based pharmacokinetic) modeling. To this end, tiss...

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Detalles Bibliográficos
Autores principales:	Fan, Yao-Yun, Farrokhi, Vahid, Caiazzo, Teresa, Wang, Mengmeng, O’Hara, Denise M., Neubert, Hendrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722552/ https://www.ncbi.nlm.nih.gov/pubmed/31443181 http://dx.doi.org/10.3390/biom9080373

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