The SRC Inhibitor Dasatinib Induces Stem Cell-Like Properties in Head and Neck Cancer Cells that are Effectively Counteracted by the Mithralog EC-8042

The frequent dysregulation of SRC family kinases (SFK) in multiple cancers prompted various inhibitors to be actively tested in preclinical and clinical trials. Disappointingly, dasatinib and saracatinib failed to demonstrate monotherapeutic efficacy in patients with head and neck squamous cell carc...

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Detalles Bibliográficos
Autores principales: Hermida-Prado, Francisco, Villaronga, M. Ángeles, Granda-Díaz, Rocío, del-Río-Ibisate, Nagore, Santos, Laura, Hermosilla, Maria Ana, Oro, Patricia, Allonca, Eva, Agorreta, Jackeline, Garmendia, Irati, Tornín, Juan, Perez-Escuredo, Jhudit, Fuente, Rocío, Montuenga, Luis M., Morís, Francisco, Rodrigo, Juan P., Rodríguez, René, García-Pedrero, Juana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722627/
https://www.ncbi.nlm.nih.gov/pubmed/31382448
http://dx.doi.org/10.3390/jcm8081157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722627/
https://www.ncbi.nlm.nih.gov/pubmed/31382448
http://dx.doi.org/10.3390/jcm8081157

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