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Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D(2) Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor

The interplay between the dopamine (DA) and opioid systems in the brain is known to modulate the additive effects of substances of abuse. On one hand, opioids serve mankind by their analgesic properties, which are mediated via the mu opioid receptor (MOR), a Class A G protein-coupled receptor (GPCR)...

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Detalles Bibliográficos
Autores principales: Vasudevan, Lakshmi, Borroto-Escuela, Dasiel O., Huysentruyt, Jelle, Fuxe, Kjell, Saini, Deepak K., Stove, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722706/
https://www.ncbi.nlm.nih.gov/pubmed/31416253
http://dx.doi.org/10.3390/biom9080368