Analytical and Computational Methods for the Estimation of Drug-Polymer Solubility and Miscibility in Solid Dispersions Development

The development of stable solid dispersion formulations that maintain desired improvement of drug dissolution rate during the entire shelf life requires the analysis of drug-polymer solubility and miscibility. Only if the drug concentration is below the solubility limit in the polymer, the physical...

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Detalles Bibliográficos
Autores principales: Medarević, Djordje, Djuriš, Jelena, Barmpalexis, Panagiotis, Kachrimanis, Kyriakos, Ibrić, Svetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722809/
https://www.ncbi.nlm.nih.gov/pubmed/31374926
http://dx.doi.org/10.3390/pharmaceutics11080372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722809/
https://www.ncbi.nlm.nih.gov/pubmed/31374926
http://dx.doi.org/10.3390/pharmaceutics11080372

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