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The Investigation of Flory–Huggins Interaction Parameters for Amorphous Solid Dispersion Across the Entire Temperature and Composition Range

Amorphous solid dispersion (ASD) is one of the most promising enabling formulations featuring significant water solubility and bioavailability enhancements for biopharmaceutical classification system (BCS) class II and IV drugs. An accurate thermodynamic understanding of the ASD should be establishe...

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Detalles Bibliográficos
Autores principales: Tian, Yiwei, Qian, Kaijie, Jacobs, Esther, Amstad, Esther, Jones, David S., Stella, Lorenzo, Andrews, Gavin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722828/
https://www.ncbi.nlm.nih.gov/pubmed/31430958
http://dx.doi.org/10.3390/pharmaceutics11080420