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SiNPle: Fast and Sensitive Variant Calling for Deep Sequencing Data
Current high-throughput sequencing technologies can generate sequence data and provide information on the genetic composition of samples at very high coverage. Deep sequencing approaches enable the detection of rare variants in heterogeneous samples, such as viral quasi-species, but also have the un...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722845/ https://www.ncbi.nlm.nih.gov/pubmed/31349684 http://dx.doi.org/10.3390/genes10080561 |