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SiNPle: Fast and Sensitive Variant Calling for Deep Sequencing Data

Current high-throughput sequencing technologies can generate sequence data and provide information on the genetic composition of samples at very high coverage. Deep sequencing approaches enable the detection of rare variants in heterogeneous samples, such as viral quasi-species, but also have the un...

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Detalles Bibliográficos
Autores principales: Ferretti, Luca, Tennakoon, Chandana, Silesian, Adrian, Freimanis, Graham, Ribeca, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722845/
https://www.ncbi.nlm.nih.gov/pubmed/31349684
http://dx.doi.org/10.3390/genes10080561