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Factorial Design as a Tool for the Optimization of PLGA Nanoparticles for the Co-Delivery of Temozolomide and O6-Benzylguanine

Poly(d,l-lactic-co-glycolic) (PLGA) nanoparticles (NPs) have been widely studied for several applications due to their advantageous properties, such as biocompatibility and biodegradability. Therefore, these nanocarriers could be a suitable approach for glioblastoma multiforme (GBM) therapy. The tre...

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Detalles Bibliográficos
Autores principales: Ramalho, Maria João, Loureiro, Joana A., Coelho, Manuel A. N., Pereira, Maria Carmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722980/
https://www.ncbi.nlm.nih.gov/pubmed/31405159
http://dx.doi.org/10.3390/pharmaceutics11080401