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The Influence of Polysaccharide Coating on the Physicochemical Parameters and Cytotoxicity of Silica Nanoparticles for Hydrophilic Biomolecules Delivery

The present work reports the effect of polysaccharides (chitosan and sodium alginate) on silica nanoparticles (SiNP) for hydrophilic molecules delivery taking insulin as model drug. The influence of tetraethyl orthosilicate (TEOS) and homogenization speed on SiNP properties was assessed by a 2(2) fa...

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Detalles Bibliográficos
Autores principales: Andreani, Tatiana, Fangueiro, Joana F., Severino, Patrícia, de Souza, Ana Luiza R., Martins-Gomes, Carlos, Fernandes, Paula M. V., Calpena, Ana C., Gremião, Maria P., Souto, Eliana B., Silva, Amélia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723031/
https://www.ncbi.nlm.nih.gov/pubmed/31357658
http://dx.doi.org/10.3390/nano9081081