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Polyelectrolyte Complexes between Polycarboxylates and BMP-2 for Enhancing Osteogenic Differentiation: Effect of Chemical Structure of Polycarboxylates

Bone morphogenetic protein 2 (BMP-2) has received considerable attention because of its osteoinductivity, but its use is limited owing to its instability and adverse effects. To reduce the dose of BMP-2, complexation with heparin is a promising approach, because heparin enhances the osteoinductivity...

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Detalles Bibliográficos
Autores principales: Terauchi, Masahiko, Tamura, Atsushi, Tonegawa, Asato, Yamaguchi, Satoshi, Yoda, Tetsuya, Yui, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723113/
https://www.ncbi.nlm.nih.gov/pubmed/31405005
http://dx.doi.org/10.3390/polym11081327