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Polyelectrolyte Complexes between Polycarboxylates and BMP-2 for Enhancing Osteogenic Differentiation: Effect of Chemical Structure of Polycarboxylates
Bone morphogenetic protein 2 (BMP-2) has received considerable attention because of its osteoinductivity, but its use is limited owing to its instability and adverse effects. To reduce the dose of BMP-2, complexation with heparin is a promising approach, because heparin enhances the osteoinductivity...
Autores principales: | Terauchi, Masahiko, Tamura, Atsushi, Tonegawa, Asato, Yamaguchi, Satoshi, Yoda, Tetsuya, Yui, Nobuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723113/ https://www.ncbi.nlm.nih.gov/pubmed/31405005 http://dx.doi.org/10.3390/polym11081327 |
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