Cargando…

Multi-Modulation of Doxorubicin Resistance in Breast Cancer Cells by Poly(l-histidine)-Based Multifunctional Micelles

Even though the reversal of multi-drug resistance (MDR) by numerous nanoparticles has been extensively studied, limited success has been achieved. To overcome this barrier, we report a rationally-designed pH-sensitive micelle, in which doxorubicin (Dox) and resveratrol (Res) were co-loaded. The mice...

Descripción completa

Detalles Bibliográficos
Autores principales: Jia, Li, Jia, Nan, Gao, Yan, Hu, Haiyang, Zhao, Xiuli, Chen, Dawei, Qiao, Mingxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723117/
https://www.ncbi.nlm.nih.gov/pubmed/31382390
http://dx.doi.org/10.3390/pharmaceutics11080385