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FERMI: A Novel Method for Sensitive Detection of Rare Mutations in Somatic Tissue

With growing interest in monitoring mutational processes in normal tissues, tumor heterogeneity, and cancer evolution under therapy, the ability to accurately and economically detect ultra-rare mutations is becoming increasingly important. However, this capability has often been compromised by signi...

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Detalles Bibliográficos
Autores principales: Liggett, L. Alexander, Sharma, Anchal, De, Subhajyoti, DeGregori, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723130/
https://www.ncbi.nlm.nih.gov/pubmed/31352405
http://dx.doi.org/10.1534/g3.119.400438