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Reprogramming of Urine-Derived Renal Epithelial Cells into iPSCs Using srRNA and Consecutive Differentiation into Beating Cardiomyocytes

The generation of induced pluripotent stem cells (iPSCs) from patient’s somatic cells and the subsequent differentiation into desired cell types opens up numerous possibilities in regenerative medicine and tissue engineering. Adult cardiomyocytes have limited self-renewal capacity; thus, the efficie...

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Detalles Bibliográficos
Autores principales: Steinle, Heidrun, Weber, Marbod, Behring, Andreas, Mau-Holzmann, Ulrike, von Ohle, Christiane, Popov, Aron-Frederik, Schlensak, Christian, Wendel, Hans Peter, Avci-Adali, Meltem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723182/
https://www.ncbi.nlm.nih.gov/pubmed/31476669
http://dx.doi.org/10.1016/j.omtn.2019.07.016