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The statistical power of k-mer based aggregative statistics for alignment-free detection of horizontal gene transfer

Alignment-based database search and sequence comparison are commonly used to detect horizontal gene transfer (HGT). However, with the rapid increase of sequencing depth, hundreds of thousands of contigs are routinely assembled from metagenomics studies, which challenges alignment-based HGT analysis...

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Detalles Bibliográficos
Autores principales: Huang, Guan-Da, Liu, Xue-Mei, Huang, Tian-Lai, Xia, Li- C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723412/
https://www.ncbi.nlm.nih.gov/pubmed/31508512
http://dx.doi.org/10.1016/j.synbio.2019.08.001