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Pharmacokinetic Profile and Anti-Adhesive Effect of Oxaliplatin-PLGA Microparticle-Loaded Hydrogels in Rats for Colorectal Cancer Treatment

Colorectal cancer (CRC) is one of the most malignant and fatal cancers worldwide. Although cytoreductive surgery combined with chemotherapy is considered a promising therapy, peritoneal adhesion causes further complications after surgery. In this study, oxaliplatin-loaded Poly-(d,l-lactide-co-glycol...

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Detalles Bibliográficos
Autores principales: Abuzar, Sharif Md, Ahn, Jun-Hyun, Park, Kyung Su, Park, Eun Jung, Baik, Seung Hyuk, Hwang, Sung-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723418/
https://www.ncbi.nlm.nih.gov/pubmed/31387217
http://dx.doi.org/10.3390/pharmaceutics11080392