Camelid VHHs Fused to Human Fc Fragments Provide Long Term Protection Against Botulinum Neurotoxin A in Mice

The bacterium Clostridium botulinum is the causative agent of botulism—a severe intoxication caused by botulinum neurotoxin (BoNT) and characterized by damage to the nervous system. In an effort to develop novel C. botulinum immunotherapeutics, camelid single-domain antibodies (sdAbs, VHHs, or nanob...

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Detalles Bibliográficos
Autores principales: Godakova, Svetlana A., Noskov, Anatoly N., Vinogradova, Irina D., Ugriumova, Galina A., Solovyev, Andrey I., Esmagambetov, Ilias B., Tukhvatulin, Amir I., Logunov, Denis Y., Naroditsky, Boris S., Shcheblyakov, Dmitry V., Gintsburg, Aleksandr L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723419/
https://www.ncbi.nlm.nih.gov/pubmed/31394847
http://dx.doi.org/10.3390/toxins11080464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723419/
https://www.ncbi.nlm.nih.gov/pubmed/31394847
http://dx.doi.org/10.3390/toxins11080464

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