Inactivation of Aldehyde Dehydrogenase by Disulfiram in the Presence and Absence of Lipoic Acid or Dihydrolipoic Acid: An in Vitro Study

The inhibition of aldehyde dehydrogenase (ALDH) by disulfiram (DSF) in vitro can be prevented and/or reversed by dithiothreitol (DTT), which is a well-known low molecular weight non-physiological redox reagent commonly used in laboratory experiments. These observations inspired us to ask the questio...

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Detalles Bibliográficos
Autores principales: Bilska-Wilkosz, Anna, Górny, Magdalena, Iciek, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723463/
https://www.ncbi.nlm.nih.gov/pubmed/31426424
http://dx.doi.org/10.3390/biom9080375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723463/
https://www.ncbi.nlm.nih.gov/pubmed/31426424
http://dx.doi.org/10.3390/biom9080375

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