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Meta-Analysis of Cancer Triploidy: Rearrangements of Genome Complements in Male Human Tumors Are Characterized by XXY Karyotypes

Triploidy in cancer is associated with poor prognosis, but its origins remain unclear. Here, we attempted to differentiate between random chromosomal and whole-genome origins of cancer triploidy. In silico meta-analysis was performed on 15 male malignant and five benign tumor cohorts (2928 karyotype...

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Detalles Bibliográficos
Autores principales: Vainshelbaum, Ninel M., Zayakin, Pawel, Kleina, Regina, Giuliani, Alessandro, Erenpreisa, Jekaterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723511/
https://www.ncbi.nlm.nih.gov/pubmed/31412657
http://dx.doi.org/10.3390/genes10080613