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Meta-Analysis of Cancer Triploidy: Rearrangements of Genome Complements in Male Human Tumors Are Characterized by XXY Karyotypes
Triploidy in cancer is associated with poor prognosis, but its origins remain unclear. Here, we attempted to differentiate between random chromosomal and whole-genome origins of cancer triploidy. In silico meta-analysis was performed on 15 male malignant and five benign tumor cohorts (2928 karyotype...
Autores principales: | Vainshelbaum, Ninel M., Zayakin, Pawel, Kleina, Regina, Giuliani, Alessandro, Erenpreisa, Jekaterina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723511/ https://www.ncbi.nlm.nih.gov/pubmed/31412657 http://dx.doi.org/10.3390/genes10080613 |
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