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New Linear Precursors of cIDPR Derivatives as Stable Analogs of cADPR: A Potent Second Messenger with Ca(2+)-Modulating Activity Isolated from Sea Urchin Eggs

Herein, we report on the synthesis of a small set of linear precursors of an inosine analogue of cyclic ADP-ribose (cADPR), a second messenger involved in Ca(2+) mobilization from ryanodine receptor stores firstly isolated from sea urchin eggs extracts. The synthesized compounds were obtained starti...

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Detalles Bibliográficos
Autores principales: D’Errico, Stefano, Basso, Emy, Falanga, Andrea Patrizia, Marzano, Maria, Pozzan, Tullio, Piccialli, Vincenzo, Piccialli, Gennaro, Oliviero, Giorgia, Borbone, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723567/
https://www.ncbi.nlm.nih.gov/pubmed/31426471
http://dx.doi.org/10.3390/md17080476