Cargando…
New Linear Precursors of cIDPR Derivatives as Stable Analogs of cADPR: A Potent Second Messenger with Ca(2+)-Modulating Activity Isolated from Sea Urchin Eggs
Herein, we report on the synthesis of a small set of linear precursors of an inosine analogue of cyclic ADP-ribose (cADPR), a second messenger involved in Ca(2+) mobilization from ryanodine receptor stores firstly isolated from sea urchin eggs extracts. The synthesized compounds were obtained starti...
Autores principales: | D’Errico, Stefano, Basso, Emy, Falanga, Andrea Patrizia, Marzano, Maria, Pozzan, Tullio, Piccialli, Vincenzo, Piccialli, Gennaro, Oliviero, Giorgia, Borbone, Nicola |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723567/ https://www.ncbi.nlm.nih.gov/pubmed/31426471 http://dx.doi.org/10.3390/md17080476 |
Ejemplares similares
-
Synthesis and Biological Evaluation of a New Structural Simplified Analogue of cADPR, a Calcium-Mobilizing Secondary Messenger Firstly Isolated from Sea Urchin Eggs
por: D’Errico, Stefano, et al.
Publicado: (2018) -
Synthesis of cyclic N(1)-pentylinosine phosphate, a new structurally reduced cADPR analogue with calcium-mobilizing activity on PC12 cells
por: Mahal, Ahmed, et al.
Publicado: (2015) -
cADPR Does Not Activate TRPM2
por: Riekehr, Winnie Maria, et al.
Publicado: (2022) -
Concise Syntheses of Trifluoromethylated Cyclic and Acyclic Analogues of cADPR
por: Huang, Xiangchen, et al.
Publicado: (2010) -
CD38/cADPR Signaling Pathway in Airway Disease: Regulatory Mechanisms
por: Deshpande, Deepak A., et al.
Publicado: (2018)