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A Mixed Thermosensitive Hydrogel System for Sustained Delivery of Tacrolimus for Immunosuppressive Therapy

Tacrolimus is an immunosuppressive agent for acute rejection after allotransplantation. However, the low aqueous solubility of tacrolimus poses difficulties in formulating an injection dosage. Polypeptide thermosensitive hydrogels can maintain a sustained release depot to deliver tacrolimus. The cop...

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Detalles Bibliográficos
Autores principales: Lin, Hsiu-Chao, Anggelia, Madonna Rica, Cheng, Chih-Chi, Ku, Kuan-Lin, Cheng, Hui-Yun, Wen, Chih-Jen, Wang, Aline Yen Ling, Lin, Cheng-Hung, Chu, I-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723608/
https://www.ncbi.nlm.nih.gov/pubmed/31416239
http://dx.doi.org/10.3390/pharmaceutics11080413