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New Monoclonal Antibodies for a Selective Detection of Membrane-Associated and Soluble Forms of Carbonic Anhydrase IX in Human Cell Lines and Biological Samples

Monoclonal antibodies (MAbs) selectively targeting tumor-associated antigens such as carbonic anhydrase IX (CA IX) can significantly contribute to research, diagnostics, and treatment of CA IX-related cancers. CA IX is overexpressed in numerous hypoxic cancers where it promotes tumor progression. Th...

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Detalles Bibliográficos
Autores principales: Stravinskiene, Dovile, Imbrasaite, Aiste, Petrikaite, Vilma, Matulis, Daumantas, Matuliene, Jurgita, Zvirbliene, Aurelija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723738/
https://www.ncbi.nlm.nih.gov/pubmed/31349673
http://dx.doi.org/10.3390/biom9080304