Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650

Background: The epithelial layer of the nasal mucosa is the first barrier for drug permeation during intranasal drug delivery. With increasing interest for intranasal pathways, adequate in vitro models are required. Here, porcine olfactory (OEPC) and respiratory (REPC) primary cells were characteris...

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Detalles Bibliográficos
Autores principales: Ladel, Simone, Schlossbauer, Patrick, Flamm, Johannes, Luksch, Harald, Mizaikoff, Boris, Schindowski, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723747/
https://www.ncbi.nlm.nih.gov/pubmed/31374872
http://dx.doi.org/10.3390/pharmaceutics11080367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723747/
https://www.ncbi.nlm.nih.gov/pubmed/31374872
http://dx.doi.org/10.3390/pharmaceutics11080367

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