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Dietary Glycotoxins, Advanced Glycation End Products, Inhibit Cell Proliferation and Progesterone Secretion in Ovarian Granulosa Cells and Mimic PCOS-Like Symptoms

Women with polycystic ovary syndrome (PCOS) have been reported to have an elevated serum advanced glycation end product (AGE) level. However, the effect of AGEs on the pathophysiological ovarian granulosa cells of PCOS is still unclear. In this study, five indented BSA-derived AGE products were used...

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Detalles Bibliográficos
Autores principales: Lin, Po-Han, Chang, Chih-Chao, Wu, Kun-Hsuan, Shih, Chun-Kuang, Chiang, Wenchang, Chen, Hsin-Yuan, Shih, Yin-Hwa, Wang, Kei-Lee, Hong, Yong-Han, Shieh, Tzong-Ming, Hsia, Shih-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723748/
https://www.ncbi.nlm.nih.gov/pubmed/31370285
http://dx.doi.org/10.3390/biom9080327