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Effects of the Q80K Polymorphism on the Physicochemical Properties of Hepatitis C Virus Subtype 1a NS3 Protease

Hepatitis C virus genotype 1a (HCV-1a) comprises clades I and II. The Q80K polymorphism is found predominantly in clade I but rarely in clade II. Here, we investigated whether natural polymorphisms in HCV-1a clade II entailed structural protein changes when occurrence of the Q80K variant was simulat...

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Detalles Bibliográficos
Autores principales: Peres-da-Silva, Allan, Antunes, Deborah, Quintanilha Torres, André Luiz, Caffarena, Ernesto Raul, Lampe, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723822/
https://www.ncbi.nlm.nih.gov/pubmed/31366046
http://dx.doi.org/10.3390/v11080691