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Designing Fast-Dissolving Orodispersible Films of Amphotericin B for Oropharyngeal Candidiasis

Amphotericin B possesses high activity against Candida spp. with low risk of resistance. However, Amphotericin B’s high molecular weight compared to other antifungal drugs, such as miconazole and clotrimazole, and poor water solubility hampers its efficacy at the physiological conditions of the orop...

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Detalles Bibliográficos
Autores principales: Serrano, Dolores R., Fernandez-Garcia, Raquel, Mele, Marta, Healy, Anne Marie, Lalatsa, Aikaterini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723921/
https://www.ncbi.nlm.nih.gov/pubmed/31374879
http://dx.doi.org/10.3390/pharmaceutics11080369