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Designing Fast-Dissolving Orodispersible Films of Amphotericin B for Oropharyngeal Candidiasis
Amphotericin B possesses high activity against Candida spp. with low risk of resistance. However, Amphotericin B’s high molecular weight compared to other antifungal drugs, such as miconazole and clotrimazole, and poor water solubility hampers its efficacy at the physiological conditions of the orop...
Autores principales: | Serrano, Dolores R., Fernandez-Garcia, Raquel, Mele, Marta, Healy, Anne Marie, Lalatsa, Aikaterini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723921/ https://www.ncbi.nlm.nih.gov/pubmed/31374879 http://dx.doi.org/10.3390/pharmaceutics11080369 |
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