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In Silico Identification of Novel Aromatic Compounds as Potential HIV-1 Entry Inhibitors Mimicking Cellular Receptor CD4

Despite recent progress in the development of novel potent HIV-1 entry/fusion inhibitors, there are currently no licensed antiviral drugs based on inhibiting the critical interactions of the HIV-1 envelope gp120 protein with cellular receptor CD4. In this connection, studies on the design of new sma...

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Detalles Bibliográficos
Autores principales: Andrianov, Alexander M., Nikolaev, Grigory I., Kornoushenko, Yuri V., Xu, Wei, Jiang, Shibo, Tuzikov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723994/
https://www.ncbi.nlm.nih.gov/pubmed/31412617
http://dx.doi.org/10.3390/v11080746