Evaluation of Tumor-Targeting Properties of an Antagonistic Bombesin Analogue RM26 Conjugated with a Non-Residualizing Radioiodine Label Comparison with a Radiometal-Labelled Counterpart

Radiolabelled antagonistic bombesin analogues are successfully used for targeting of gastrin-releasing peptide receptors (GRPR) that are overexpressed in prostate cancer. Internalization of antagonistic bombesin analogues is slow. We hypothesized that the use of a non-residualizing radioiodine label...

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Detalles Bibliográficos
Autores principales: Oroujeni, Maryam, Abouzayed, Ayman, Lundmark, Fanny, Mitran, Bogdan, Orlova, Anna, Tolmachev, Vladimir, Rosenström, Ulrika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724035/
https://www.ncbi.nlm.nih.gov/pubmed/31382362
http://dx.doi.org/10.3390/pharmaceutics11080380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724035/
https://www.ncbi.nlm.nih.gov/pubmed/31382362
http://dx.doi.org/10.3390/pharmaceutics11080380

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