Biotransformation of the Mycotoxin Enniatin B1 by CYP P450 3A4 and Potential for Drug-Drug Interactions

Enniatins (ENNs) are fungal secondary metabolites that frequently occur in grain in temperate climates. Their toxic potency is connected to their ionophoric character and lipophilicity. The biotransformation of ENNs predominantly takes place via cytochrome P450 3A (CYP 3A)-dependent oxidation reacti...

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Detalles Bibliográficos
Autores principales: Ivanova, Lada, Denisov, Ilia G., Grinkova, Yelena V., Sligar, Stephen G., Fæste, Christiane K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724072/
https://www.ncbi.nlm.nih.gov/pubmed/31357617
http://dx.doi.org/10.3390/metabo9080158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724072/
https://www.ncbi.nlm.nih.gov/pubmed/31357617
http://dx.doi.org/10.3390/metabo9080158

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