Assessing the Justification, Funding, Success, and Survival Outcomes of Randomized Noninferiority Trials of Cancer Drugs: A Systematic Review and Pooled Analysis

IMPORTANCE: Noninferiority trials test whether a new intervention is not worse than the comparator by a given margin. OBJECTIVES: To study the characteristics of published randomized noninferiority trials in oncology with overall survival as an end point, to assess the association of justification a...

Descripción completa

Detalles Bibliográficos
Autores principales: Gyawali, Bishal, Tessema, Frazer A., Jung, Emily H., Kesselheim, Aaron S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2019
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724156/
https://www.ncbi.nlm.nih.gov/pubmed/31469391
http://dx.doi.org/10.1001/jamanetworkopen.2019.9570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724156/
https://www.ncbi.nlm.nih.gov/pubmed/31469391
http://dx.doi.org/10.1001/jamanetworkopen.2019.9570

Ejemplares similares