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Long non-coding RNA HOTAIR modulates intervertebral disc degenerative changes via Wnt/β-catenin pathway

BACKGROUND: Intervertebral disc degeneration (IDD) has a complicated and enigmatic pathogenic process. Accumulating evidence shows that long non-coding RNAs (LncRNAs) play a role in the pathogenesis of IDD. This study aimed to investigate the expression and role of the LncRNA HOTAIR in IDD pathogene...

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Detalles Bibliográficos
Autores principales: Zhan, Shengfeng, Wang, Kun, Song, Yu, Li, Shuai, Yin, Huipeng, Luo, Rongjin, Liao, Zhiwei, Wu, Xinghuo, Zhang, Yukun, Yang, Cao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724301/
https://www.ncbi.nlm.nih.gov/pubmed/31481088
http://dx.doi.org/10.1186/s13075-019-1986-8