High numbers of activated helper T cells are associated with better clinical outcome in early stage vulvar cancer, irrespective of HPV or p53 status

BACKGROUND: Vulvar squamous cell carcinoma (VSCC) has been suggested to consist of three subtypes; HPV-positive, HPV-negative mutated TP53 or HPV-negative TP53 wildtype, with different clinical courses. To analyze the immune infiltrate in these molecular subtypes and its impact on clinical outcome,...

Descripción completa

Detalles Bibliográficos
Autores principales: Kortekaas, Kim E., Santegoets, Saskia J., Abdulrahman, Ziena, van Ham, Vanessa J., van der Tol, Marij, Ehsan, Ilina, van Doorn, Helena C., Bosse, Tjalling, van Poelgeest, Mariëtte I. E., van der Burg, Sjoerd H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724316/
https://www.ncbi.nlm.nih.gov/pubmed/31481117
http://dx.doi.org/10.1186/s40425-019-0712-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724316/
https://www.ncbi.nlm.nih.gov/pubmed/31481117
http://dx.doi.org/10.1186/s40425-019-0712-z

Ejemplares similares