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Enasidenib in acute myeloid leukemia: clinical development and perspectives on treatment

Recently there has been a significant progression in the understanding of molecular mutations driving biochemical and cellular signaling changes leading to survival and proliferation of leukemia cells in patients with acute myeloid leukemia (AML). Preclinical studies have demonstrated a mutated enzy...

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Detalles Bibliográficos
Autores principales: Reed, Daniel R, Elsarrag, Ramey Z, Morris, Amy L, Keng, Michael K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724422/
https://www.ncbi.nlm.nih.gov/pubmed/31564968
http://dx.doi.org/10.2147/CMAR.S162784