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The P5A ATPase Spf1p is stimulated by phosphatidylinositol 4-phosphate and influences cellular sterol homeostasis

P5A ATPases are expressed in the endoplasmic reticulum (ER) of all eukaryotic cells, and their disruption results in severe ER stress. However, the function of these ubiquitous membrane proteins, which belong to the P-type ATPase superfamily, is unknown. We purified a functional tagged version of th...

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Detalles Bibliográficos
Autores principales: Sørensen, Danny Mollerup, Holen, Henrik Waldal, Pedersen, Jesper Torbøl, Martens, Helle Juel, Silvestro, Daniele, Stanchev, Lyubomir Dimitrov, Costa, Sara Rute, Günther Pomorski, Thomas, López-Marqués, Rosa Laura, Palmgren, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724510/
https://www.ncbi.nlm.nih.gov/pubmed/30785834
http://dx.doi.org/10.1091/mbc.E18-06-0365