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Matured Tolerogenic Dendritic Cells Effectively Inhibit Autoantigen Specific CD4(+) T Cells in a Murine Arthritis Model

Tolerogenic dendritic cells (tolDCs) are a promising treatment modality for diseases caused by a breach in immune tolerance, such as rheumatoid arthritis. Current medication for these diseases is directed toward symptom suppression but no real cure is available yet. TolDC-based therapy aims to resto...

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Detalles Bibliográficos
Autores principales: Jansen, Manon A. A., Spiering, Rachel, Ludwig, Irene S., van Eden, Willem, Hilkens, Catharien M. U., Broere, Femke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724516/
https://www.ncbi.nlm.nih.gov/pubmed/31555285
http://dx.doi.org/10.3389/fimmu.2019.02068