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CEP135 isoform dysregulation promotes centrosome amplification in breast cancer cells
The centrosome, composed of two centrioles surrounded by pericentriolar material, is the cell’s central microtubule-organizing center. Centrosome duplication is coupled with the cell cycle such that centrosomes duplicate once in S phase. Loss of such coupling produces supernumerary centrosomes, a co...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724517/ https://www.ncbi.nlm.nih.gov/pubmed/30811267 http://dx.doi.org/10.1091/mbc.E18-10-0674 |