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CEP135 isoform dysregulation promotes centrosome amplification in breast cancer cells

The centrosome, composed of two centrioles surrounded by pericentriolar material, is the cell’s central microtubule-organizing center. Centrosome duplication is coupled with the cell cycle such that centrosomes duplicate once in S phase. Loss of such coupling produces supernumerary centrosomes, a co...

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Detalles Bibliográficos
Autores principales:	Ganapathi Sankaran, Divya, Stemm-Wolf, Alexander J., Pearson, Chad G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724517/ https://www.ncbi.nlm.nih.gov/pubmed/30811267 http://dx.doi.org/10.1091/mbc.E18-10-0674

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