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ELMOD2 regulates mitochondrial fusion in a mitofusin-dependent manner, downstream of ARL2

Mitochondria are essential and dynamic organelles undergoing constant fission and fusion. The primary players in mitochondrial morphology (MFN1/2, OPA1, DRP1) have been identified, but their mechanism(s) of regulation are still being elucidated. ARL2 is a regulatory GTPase that has previously been s...

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Detalles Bibliográficos
Autores principales: Schiavon, Cara R., Turn, Rachel E., Newman, Laura E., Kahn, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724520/
https://www.ncbi.nlm.nih.gov/pubmed/30865555
http://dx.doi.org/10.1091/mbc.E18-12-0804