Proinflammatory Differentiation of Macrophages Through Microparticles That Form Immune Complexes Leads to T- and B-Cell Activation in Systemic Autoimmune Diseases

Patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) demonstrate increased circulating microparticles (MP). These vesicles, primarily those that form immune complexes (MP-IC), may activate monocytes. We evaluated the effect of MP and MP-IC in the differentiation of monocyte...

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Detalles Bibliográficos
Autores principales: Burbano, Catalina, Villar-Vesga, Juan, Vásquez, Gloria, Muñoz-Vahos, Carlos, Rojas, Mauricio, Castaño, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724570/
https://www.ncbi.nlm.nih.gov/pubmed/31555283
http://dx.doi.org/10.3389/fimmu.2019.02058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724570/
https://www.ncbi.nlm.nih.gov/pubmed/31555283
http://dx.doi.org/10.3389/fimmu.2019.02058

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