Continuous Developmental and Early Life Trichloroethylene Exposure Promoted DNA Methylation Alterations in Polycomb Protein Binding Sites in Effector/Memory CD4(+) T Cells

Trichloroethylene (TCE) is an industrial solvent and drinking water pollutant associated with CD4(+) T cell-mediated autoimmunity. In our mouse model, discontinuation of TCE exposure during adulthood after developmental exposure did not prevent immunotoxicity. To determine whether persistent effects...

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Detalles Bibliográficos
Autores principales: Byrum, Stephanie D., Washam, Charity L., Patterson, John D., Vyas, Kanan K., Gilbert, Kathleen M., Blossom, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724578/
https://www.ncbi.nlm.nih.gov/pubmed/31555266
http://dx.doi.org/10.3389/fimmu.2019.02016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724578/
https://www.ncbi.nlm.nih.gov/pubmed/31555266
http://dx.doi.org/10.3389/fimmu.2019.02016

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