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Structure Based Prediction of Neoantigen Immunogenicity

The development of immunological therapies that incorporate peptide antigens presented to T cells by MHC proteins is a long sought-after goal, particularly for cancer, where mutated neoantigens are being explored as personalized cancer vaccines. Although neoantigens can be identified through sequenc...

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Detalles Bibliográficos
Autores principales: Riley, Timothy P., Keller, Grant L. J., Smith, Angela R., Davancaze, Lauren M., Arbuiso, Alyssa G., Devlin, Jason R., Baker, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724579/
https://www.ncbi.nlm.nih.gov/pubmed/31555277
http://dx.doi.org/10.3389/fimmu.2019.02047