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Drosophila p53 directs nonapoptotic programs in postmitotic tissue

TP53 is the most frequently mutated gene in human cancers, and despite intensive research efforts, genome-scale studies of p53 function in whole animal models are rare. The need for such in vivo studies is underscored by recent challenges to established paradigms, indicating that unappreciated p53 f...

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Detalles Bibliográficos
Autores principales: Kurtz, Paula, Jones, Amanda E., Tiwari, Bhavana, Link, Nichole, Wylie, Annika, Tracy, Charles, Krämer, Helmut, Abrams, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724604/
https://www.ncbi.nlm.nih.gov/pubmed/30892991
http://dx.doi.org/10.1091/mbc.E18-12-0791