IRSp53 coordinates AMPK and 14-3-3 signaling to regulate filopodia dynamics and directed cell migration

Filopodia are actin-filled membrane protrusions that play essential roles in cell motility and cell–cell communication and act as precursors of dendritic spines. IRSp53 is an essential regulator of filopodia formation, which couples Rho-GTPase signaling to actin cytoskeleton and membrane remodeling....

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Detalles Bibliográficos
Autores principales: Kast, David J., Dominguez, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724608/
https://www.ncbi.nlm.nih.gov/pubmed/30893014
http://dx.doi.org/10.1091/mbc.E18-09-0600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724608/
https://www.ncbi.nlm.nih.gov/pubmed/30893014
http://dx.doi.org/10.1091/mbc.E18-09-0600

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