Discovering human transcription factor physical interactions with genetic variants, novel DNA motifs, and repetitive elements using enhanced yeast one-hybrid assays

Identifying transcription factor (TF) binding to noncoding variants, uncharacterized DNA motifs, and repetitive genomic elements has been technically and computationally challenging. Current experimental methods, such as chromatin immunoprecipitation, generally test one TF at a time, and computation...

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Detalles Bibliográficos
Autores principales: Shrestha, Shaleen, Sewell, Jared Allan, Santoso, Clarissa Stephanie, Forchielli, Elena, Carrasco Pro, Sebastian, Martinez, Melissa, Fuxman Bass, Juan Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724672/
https://www.ncbi.nlm.nih.gov/pubmed/31481462
http://dx.doi.org/10.1101/gr.248823.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724672/
https://www.ncbi.nlm.nih.gov/pubmed/31481462
http://dx.doi.org/10.1101/gr.248823.119

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